Click here for Animal Shelters & Rescues in the Upstate.

A Child's Haven offers programs designed to provide a rich, warm, loving, and supportive, family-like environment where your child may develop socially, emotionally, physically and intellectually.

Affirm serves the entire nine-county area known as the Upstate and provides a safe place where GLBTQ youth meet and form friendships, build positive self esteem, and develop skills necessary for dealing with a negative environment.

AID Upstate is an AIDS Service Organization serving Upstate South Carolina (Anderson, Oconee, Pickens and Greenville counties). Currently, AU serves, on average, 750+ clients and families touched by HIV/AIDS.

Alston Wilkes Society provides support services to adult and juvenile offenders, former offenders and the homeless. Services include case management, employment assistance and referrals to other resources as needed. For more information, or the office closest to you, call our main office at (803) 799-2490.

Alzheimer's Association - Upstate SC Chapter
The Alzheimer's Association--Upstate South Carolina Chapter-- is a non-profit charitable tax-exempt, voluntary health organization dedicated to family support, education, research, and advocacy. The National headquarter is located in Chicago. There are approximately 4.5 million persons affected by Alzheimer's Disease or related dementia in the United States. It is estimated that 50,000 of those are in SC. Call 864-250-0029 in Greenville and 800-273-2555 in Anderson.

American Cancer Society - 864-591-0004, 864-989-8010, 800-237-6914

American Leprosy Missions is the oldest and largest U.S. organization devoted to restoring the lives of people affected by leprosy, is a non-denominational Christian non-profit organization. We support projects throughout Asia, Africa, and Latin America. Located in downtown Greenville, we need volunteers for switchboard relief, mailings, general clerical, and maintenance.

American Red Cross - Upstate Chapter
Serving Greenville and Laurens counties. Call 864-271-8222 in Greenville and 864-938-6306 in Clinton.

Anderson Crisis Life Pregnancy Center - 864-231-0077

Bethany Christian Services
Bethany is widely known as an adoption agency, but our Christian care extends to people struggling with unplanned pregnancies, infertility, and a multitude of other challenges. For more than sixty years, Bethany has responded with compassion, integrity, and commitment to the needs of children and families.

The Blood Connection
The Blood Connection has been serving the Greenville area for 25 years, working to ensure that healthcare partners have an adequate, safe, cost-effective blood supply.

Birthright Emergency Pregnancy Line - 1-800-550-4900 or 864-281-7677.

Calvary Home for Children
The mission of Calvary Home for Children in Anderson, SC is to present the hope of Christ to children who are without adequate family structure and in need of a long-term, Christ-centered home.

Carolina Pregnancy Center for Children
Offering compassionate support to women who are experiencing unplanned pregnancies. Confidential and personal counseling. Help with physical needs.

CARY Center
Our mission is to assist families in the Upstate of South Carolina that are experiencing difficulty as a result of the behavior of an adolescent member through excellence in therapeutic modalities and psychoeducation.

Commission for the Blind - South Carolina
The South Carolina Commission for the Blind is a state agency created to provide rehabilitation services, adjustment to blindness training, prevention of blindness, independent living services and various other services to blind and severely visually impaired citizens of South Carolina.

Community Food Bank of the Piedmont is an umbrella organization serving as a central distribution warehouse for hundreds of food pantries, emergency shelters, churches, food kitchens and other ministries across the Upstate. Through our network agencies, The Community Food Bank of the Piedmont is able to reach the nearly 175,000 hungry individuals living in the ten (10) counties we serve. Among this harsh figure, nearly 60,000 are children.

Connie Maxwell Children's Home provides hope for children and families dealing with difficult situations in their lives. This residential childcare ministry is headquartered in Greenwood, SC with four other campuses across the state.

CRISISline is a 24/7 telephone service that offers respect, information, & crisis intervention for anyone struggling with the choices & demands of life.  CRISISline is currently accepting volunteer applications.  Applicants should be willing to commit to 30-40 hours of training & be reliable.  Please contact volunteer@mhagc.org or call 467-3348 for information.

Crossroads Group Home for Girls
Crossroads Group Home programs facilitate emotional healing and growth, physical health, basic education, restorative independent living skills, social and recreational functioning and vocational pursuit. For those served who are emotionally handicapped, the emphasis is on the restorative and/or establishment of competence.

Daily Bread Ministries
This Greer, SC Soup Kitchen is a nonprofit, charitable organization operated solely by volunteers. The soup kitchen was created when concerned citizens in the Greer area saw the people in their town were going hungry.

Down Syndrome Family Alliance of Greenville welcomes you to join in honoring the lives and potential of adults and children with Down syndrome.

Easter Seals South Carolina - 864-232-4185

Endometriosis Association Support Group for the Upstate is for women who have endometriosis and would like to come together to discuss tips on how to deal with endo.  Please email UpstateSCEndoAssn@hotmail.com for more information.

Family Preservation & Child Welfare Network
The Mission of this web site is to improve the quality of life for families and children by advocating information sharing to create positive changes.

First Steps
South Carolina First Steps to school Readiness ('First Steps') is a comprehensive, results-oriented statewide education initiative to help prepare our children to reach first grade healthy and ready to succeed.

• Anderson Count First Steps, call 864-222-0410.
• Greenville County First Steps, call 864-467-3239.
• Oconee County First Steps, call 864-882-3236.
• Pickens County First Steps, call 864-654-3000.

GAIHN (Greenville Area Interfaith Hospitality Network) works to assist local congregations to share hospitality (in the form of emergency lodging and meals) with homeless families, and to help those families achieve self-sufficiency and self-fulfillment.

Generations Group Homes, Inc. works with troubled boys ages 10-19. Call 874-243-5557.

Goodwill Industries of Upper SC, Inc. helps people with disabilities and special needs become fully independent citizens through training and employment leading to job placement. It provides rehabilitation service, training, work adjustment, employment opportunity, and placement in competitive industry for people with disabilities and special needs. Call 864-467-3200 for more information.

Greenville Commission for the Prevention of Teen Pregnancy
The Greenville Council for the Prevention of Teen Pregnancy is a community education agency which advocates and supports programs and strategies that reduce the incidence of adolescent pregnancy.

Greenville Forward is a non-political, non-profit organization which shepherds, champions, and facilitates achieving Greenville Vision 2025 goals and initiatives. The Vision focuses on sixteen areas such as the arts, government, transportation, healthcare, environment, education, and even coolness. For more information, embrace the vision and learn more at www.greenvilleforward.com, or call Russell Stall at 233-8443.

Greenville Literacy Association
The mission of Greenville Literacy Association is to empower adults to participate more effectively in the community by providing quality instruction in reading, writing, math and speaking English. Call 467-3456 for more information.

Greenville Rape Crisis and Child Abuse Center
Greenville Rape Crisis and Child Abuse Center (GRCCAC) provides programs for the treatment, support and advocacy of child, teen and adult survivors of sexual assault, childhood sexual abuse and child abuse. Services include a 24/7 hotline, accompaniment to the ER for sexual assault victims, therapy, support groups, educational programs, parent education and support groups and more. Walk-ins welcome. 24/7 Hotline: 864-467-3633; Administrative offices: 864-331-0560.

Greer Community Ministries serves and supports its elderly neighbors who are unable to prepare or secure food for themselves through our Mobile Meals program. The organization also provides a Senior Dining program and transportation as an outlet for those facing isolation and provides emergency food and clothing assistance for the disadvantaged within the Greater Greer area.

Habitat for Humanity of Greenville County is a Christian housing ministry building simple, affordable homes for deserving, needy families. Habitat homeowners buy their homes at cost with a 20 year, interest free loan - and must perform 400 hours of "sweat equity" building their own home or other Habitat homes. We provide a "hand up" instead of a "hand out".

Hands On Greenville
Hands On Greenville was founded ten years ago in response to this challenge, with the goal of creating, organizing, and leading meaningful service projects that positively impact Greenville County. For additional information, visit Hands On Greenville.

International Center of the Upstate
The International Center of the Upstate promotes cross culture understanding between international and local members of the Upstate. We offer language classes, social clubs, English conversation classes, as well as an active International Women's Club. We can be contacted at info@internationalupstate.org.

Iron Disorders Institute
Iron Disorders Institute exists so that people with iron disorders receive early, accurate diagnosis, appropriate treatment and are equipped to live in good health. Iron disorders are conditions of Iron-Out-of-Balance™ : iron deficiency anemia, anemia of inflammation, iron overload and iron overload with anemia. Abnormal iron levels can be fatal. Also visit www.hemochromatosis.org.

Lutheran Family Services offers adoption services, foster care, family counseling, and more. Call 864-848-3804.

MEALS ON WHEELS of Greenville
MEALS ON WHEELS is a home-delivered hot meal service for persons who are unable to prepare their own food, primarily the frail elderly who are confined to their homes.

Mental Health Association of Greenville - TEENline
Call 864-467-3344, TEENline: 864-467-TEEN (467-8336).

Miracle Hill Minsitries exists that those most in need receive food, shelter, and compassion while hearing the gospel of Jesus Christ and becoming productive members of society. The motto is, "If you cannot find a friend in the world, you can find one here".

Muscular Dystrophy Association - 864-241-7980

National Multiple Sclerosis Society 1-800-FIGHTMS
The mission of the National Multiple Sclerosis Society is to end the devastating effects of MS.

Operation Andrew Ministry - 864-242-2911

Parentwise is a network of Parent Resource Centers located in Beaufort, Florence, Greenville, Lexington, and York Counties with the administrative office in Columbia. Some of the resources provided for parents by each center may be: home visitation to assist with effective parenting; pre-school kids clubs; pregnant and parenting teens groups; and fathers groups.

Partners for a Heathy Community works to improve the health and well-being of the people of Anderson, SC and the surrounding counties.

Pendleton Place Children's Shelter
The mission of the Shelter is to facilitate residential care programs in Greenville County, South Carolina, for children and youth, including, but not limited to, children who are abused, neglected or abandoned, who have run away from home, whose parents are injured or incarcerated, or who are otherwise without parental care.

Phyllis Wheatley Association
Started by Hattie Logan Duckett in 1919, the Phillis Wheatley Association was an organization that originally provided a social academic center for young African American women in Greenville, South Carolina. Today, 83 years later, the Phillis Wheatley Association caters to the needs of a diverse population throughout Greenville County and offers a wide range of services from serving meals to senior citizens to caring for preschoolers in a daycare program, from providing a Repertory Youth Theater for creative expression to hosting a nationally credentialed Big Brothers Big Sisters of America.

Piedmont Women's Center
Free and confidential services include, but are not limited to: free pregnancy tests with immediate results and confidential counseling; a safe and secure place to talk about your feelings and explore all your alternatives; limited ultrasounds through your first trimester; referrals for medical and legal aid and information; and information and counceling about sexually transmitted diseases.

Red Ribbon Works
Red Ribbon Works is a parent-based community coalition, designed to get parents involved because they are the first line of defense in keeping kids off drugs. The coalition makes the community aware of the need to prevent and intervene on an ongoing basis.

Rape Crisis Centers of South Carolina gives help to victims of rape in South Carolina. Call 803-467-3633 for more information.

Ronald McDonald House is working to better the lives of children and their families around the world. The three core programs of RMHC - the Ronald McDonald House, Ronald McDonald Family Room and Ronald McDonald Care Mobile - are focused on helping families in need. Call 864-235-0506 for more information.

Sable Rescue, Inc. is located in Greenville South Carolina. The organization pull sanimals under death sentence from animal control and shelters who do not have room for them any longer, and keeps the animals until a home can be found for them. Sable Rescue supports spay and neuter programs.

Safe Harbor, Inc. helps with emergency shelter, counseling, case management, and other related services to victims of domestic violence and their children. The local hotline is 864-467-3636; the toll-free hotline number is 800-291-2139.

SC Ovarian Cancer Foundation
This is an organization brought together by ovarian cancer patients, healthcare providers, and other concerned individuals for the dissemination of information about ovarian cancer. It has been designed for the patients, for support, for education of the public and healthcare providers, and for the furthering of research in ovarian cancer in the state of South Carolina. The Foundation has affiliations with major gynecologic oncology centers in this state.

SHARE
Sunbelt Human Advancement Resources, Inc. (SHARE) is a Community Action Agency (CAA) serving Greenville, Anderson, Pickens and Oconee counties. We are a non-profit agency that provides a wide range of services to low and moderate-income residents in upstate South Carolina. The mission of SHARE is to help low-income individuals, families, and neighborhoods become self-sufficient.

Shepherd's Gate has earned a reputation in Northern California for rebuilding shattered lives. Since 1984, we have helped over 7,600 battered and homeless women and children. Call 864-268-4357 for more information.

Shiphrah Ministries is a maternity home for girls under 21 in Belton, SC. Call 864 338-4673 for more information.

For nearly 40 years, The South Carolina Centers for Equal Justice, and its predecessors, through its offices in Anderson, Greenville and Spartanburg have been providing free civil legal assistance to the low income community in the Upstate. Call toll-free, 1-888-346-5592.
303 East River Street, Anderson
701 South Main Street, Greenville
148 East Main Street, Spartanburg

South Carolina RSD Association
(Reflex Sympathetic Dystrophy), Greenville Chapter.

Sterling Community Center offers a variety of programs for youth, including after-school programs, intramural basketball, and special events.

United Minsitries is an extension of the servant ministry of local cooperating congregations. United Ministries assists poor people in emerging from hurting situations by providing for basic needs and by creating environments which allow people to make positive life changes.

United Way of Anderson County

United Way of Greenville County
Since 1922, United Way of Greenville County has been a caring force in our community, working to identify our community's most critical needs, then ensuring that programs are in place to impact those needs. United Way, its volunteers, and 46 community partner agencies, work together to get results by building a healthier, stronger community - changing lives throughout Greenville County for the better.

Upstate Homeless Coalition
The Upstate Homeless Coalition of South Carolina is a private, non-profit organization. UHCSC is a collaborative organization dedicated to ending homelessness through programming, advocacy, and building safe and affordable housing.

Urban League of the Upstate
The Urban League of the Upstate is a non-profit organization committed to the principle of equal opportunity for all citizens in housing, education, employment, and economic development, without regard to race or socioeconomic status.

Women Build 
Women Build, a subsection of Habitat for Humanity, is a group of all-women volunteers who unite each year to raise funds and gather workers (female only) to build a home for a needy single woman with children. 

Battered Woman/Domestic Violence Hotline
Help is only a phone call away....1-800-334-2836.

Killingsworth, Inc.
Columbia, SC
Killingsworth is a transitional home for women emerging from crisis situations. The home serves women from across the southeast, including Greenville, Anderson, Oconee, Pickens, and surrounding counties.

Operation Comfort
Fort Gordon, Augusta, GA
Operation Comfort is a special program in Army Community Service (ACS) that was established to support deployed service members and their families. Support through Operation Comfort may come in the form of respite childcare, outings or other events that boost morale, family members directly purchasing goods for service members and their families. Call 1-877-310-5741 for more information.

Safe Homes - Rape Crisis Coalition
Spartanburg, SC
Safe Home - Rape Crisis serves Spartanburg, Cherokee, and Union Counties, giving help, support, and emergency shelter to victims of rape and domestic violence and their children.

Southside Unity in the Community
Spartanburg, SC
Southside Unity in the Community is dedicated to promoting volunteerism within the Southside community. The program intends to make available in one central location resources, training and opportunities that will encourage volunteerism. Southside Unity in the Community strives to lead by example. Volunteerism is rarely taught in the Southside Community; it is our hope that this program managed entirely by volunteers will inspire volunteerism in present and future generations. Call 864-621-7209 for more information.

SC Association of Nonprofit Organizations
Columbia, SC
The mission of the S.C. Association of Nonprofit Organizations (SCANPO) is to serve, support and strengthen nonprofit organizations for a better South Carolina. SCANPO's website features a search of all member nonprofit agencies, including social service organizations.

SC Center for Grassroots & Nonprofit Leadership
Clemson, SC
The Center seeks to actively build capacity and enhance resources of community and faith-based grassroots groups, nonprofit organizations, and individuals that are challenged to provide leadership and improve community life.

SC Department of Social Services
Columbia, SC
This state agency offers servies and support for families and children.

For information about additional service organizations in the Upstate, visit Spartanburg.com .